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Such an array of SARS-CoV-2 interactions with Hb could induce hemolysis and/or form complexes with released heme, generate dysfunctional Hb (hemoglobinopathy) with reduced ability to transport O 2 /CO 2 and lead to O 2 deprived multi-faceted syndromes, including coagulation disorders 146,150

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TB-500 is a synthetic peptide based on Thymosin Beta-4 (T4), a naturally occurring 43-amino-acid actin-binding protein